# 賽諾生物的基因合成與無細胞蛋白表達工作流程被騰訊生命科學人工智慧實驗室近期研究採用。

*genai, biotech · news · 2026-05-28 · PR Newswire UK*

## Key points

- 騰訊生命科學人工智慧實驗室使用賽諾生物的試劑盒快速驗證人工智慧設計的蛋白質。
- 該研究提出本體強化迭代（ORI）框架，整合實驗室反饋與人工智慧。
- 在此過程中設計出活性提升超過100倍的溶菌酶及熱穩定酶。
- XPressMAX™ 試劑盒可在短短3小時內完成蛋白質表達，具備高篩選效率。

HOUSTON, May 28, 2026 /PRNewswire/ -- Sino Biological, Inc. (Shenzhen Stock Exchange: 301047.SZ) has announced that its gene synthesis and cell-free protein expression workflow was used in a recent study by Tencent AI for Life Sciences Lab published in Nature Communications, enabling rapid validation of AI-designed proteins with improved activity, stability, and multifunctionality. Bridging AI Protein Design and Experimental Validation Artificial intelligence has accelerated protein amino acid sequence design; however, translating these computational designs into functional proteins remains a key challenge in protein engineering. Protein activity, stability, folding, and expression are influenced by complex structural and biochemical factors, often causing discrepancies between in silico predictions and experiments. To address this gap, the study introduced an Ontology Reinforcement Iteration (ORI) framework, integrating protein ontology with reinforcement learning from wet-lab feedback. Experimental data, including protein expression levels and functional activity, were continuously fed back into the model enabling iterative optimization of protein sequences and improved design accuracy. Cell-Free Protein Synthesis Accelerates the AI Design Loop The researchers subsequently utilized Sino Biological's XPressMAX™ Cell-Free Protein Synthesis Kit to enable rapid protein expression and functional screening. Protein-coding sequences cloned into the kit's expression vector and added to the proprietary cell-free reaction system supported rapid design–build–test cycles. Using this workflow, the team engineered a lysozyme with over 100-fold higher activity than the natural enzyme, developed a thermostable chitinase retaining activity at 85°C, and expressed bifunctional enzymes with improved performance compared with naturally occurring multifunctional enzymes. XPressMAX™Cell-Free Protein Synthesis Kit Key features include: Ultra-fast synthesis: proteins expressed in as little as 3 hours High screening efficiency: optimized for VHH, scFv, and miniproteins Flexible template support: compatible with plasmid and linear DNA templates Disulfide bond friendly: enables expression of complex disulfide-bonded proteins without additional enhancers Cost-effective performance: reduced operational time and cost Scalable supply: suitable for high-throughput and industrial applications About Sino Biological Sino Biological is an international reagent supplier and CRO service provider specializing in recombinant protein production and antibody development. With the US-based Center for Bioprocessing (C4B) in Houston and SignalChem Biotech (part of Sino Biological) in Canada, Sino Biological delivers tailored, localized solutions to meet diverse research needs worldwide. Serving researchers in over 90 countries, the company maintains a stringent quality management system across all products.

**Companies:** Sino Biological
**Countries:** China, United States, Canada

[Read the full story on PR Newswire UK](https://www.prnewswire.co.uk/news-releases/sino-biologicals-cell-free-protein-synthesis-supports-tencent-ai-for-life-sciences-labs-protein-design-study-published-in-nature-communications-302784203.html)

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