# Takeda Pharmaceutical, the largest life sciences employer in Massachusetts, plans to eliminate approximately 4,500 jobs globally by March 2027.

*biotech · news · 2026-05-13 · MassLive*

## Key points

- Takeda will cut 4,500 jobs globally by March 2027 as part of its Transformation Program.
- It remains unclear whether the 247 Massachusetts layoffs are included in the 4,500 global cuts.
- Job reductions are linked to a 43% global drop in VYVANSE revenue after its U.S. patent expired.
- Takeda will redirect savings toward launching three experimental drugs, two of which are under FDA priority review.

**Companies:** Takeda Pharmaceutical
**Countries:** Japan, United States

[Read the full story on MassLive](https://www.masslive.com/news/2026/05/takeda-is-laying-off-4500-by-years-end-with-hundreds-of-mass-employees-on-the-line.html)

---

Canonical: https://newsio.io/n/969bd3ef-0253-438d-8170-1375312f5f8a/takeda-pharmaceutical-the-largest-life-sciences-employer-in-massachusetts-plans
Summarized by Newsio from MassLive. https://newsio.io/how-it-works