biotech / news / / Benzinga
Takeda notified Denali Therapeutics regarding the termination of their collaboration agreement to co-develop DNL593.
Takeda has terminated its partnership with Denali for DNL593 for strategic, not safety, reasons.
KEY POINTS
- Denali regains full control and intellectual property rights for DNL593 after Takeda's exit.
- Phase 1/2 trial results for DNL593 are expected to be reported by the end of 2026.
- Early trial data show DNL593 increases cerebrospinal fluid progranulin in a dose-dependent manner.
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